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During pregnancy and breastfeeding, the demand for B vitamins, particularly folate (vitamin B9), escalates due to its role in reducing the risk of birth defects and supporting foetal growth

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NNMT inhibition produces metabolic effects including increased NAD+ levels and reduced lipogenesis

Lipid Metabolism & 3-AR Mechanism Heffernan et al., Endocrinology (2001) Heffernan and colleagues investigated the lipolytic effects of chronic AOD-9604 treatment using two complementary mouse models: diet-induced obese C57BL/6J mice and beta3 adrenergic receptor (3-AR) knockout mice