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doi: 10.1089/ars.2011.4372

Currently, there is a lack of robust clinical data supporting the safety and efficacy of glutathione injections for skin-lightening purposes, which raises concerns about their long-term impact on natural melanin production

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In contrast, iTregs arise in the periphery, where cytokines such as TGF- and IL-2 promote their antigen-induced Foxp3 expression and suppressive function, thereby establishing tolerance to foreign antigens

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