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After smoking, nicotine quickly enters the bloodstream through the lungs and spreads to the brain, where it binds to the nicotinic acetylcholine receptor (nAChR), which has a high affinity for nicotine, and triggers the release of various neurotransmitters, in particular dopamine

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Conclusion Understanding the differences in nicotine content in cigarettes and nicotine content in vapes is essential for anyone using these products