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KPNA6 (Importin 7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response

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Transport across the BBB may be facilitated by sodium-dependent transport system [76] or converting cysteine to cystine, which is subsequently exchanged with intracellular glutamate via the cystine-glutamate antiporter, and reduced back to cysteine for GSH production [115, 116]

Their results revealed the detection of 13 metabolites associated with the Hcy metabolic pathway in the samples