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Scientific References: Gwyer D, Wragg NM, Wilson SL., Cell and Tissue Research , 2019

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Cardiovascular side effects, while less common, may include changes in heart rate, with some patients experiencing a mild increase in resting heart rate of two to three beats per minute on average

Summary: Vitamin B12 toxicity from supplementation is extremely rare, but persistently elevated serum levels may indicate underlying liver disease, kidney dysfunction, or haematological disorders requiring medical investigation