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- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)

Yen & Hsieh, 1997), dopamine is easily oxidized and generates highly reactive metabolites such as dopamine quinone, which further lead to mitochondrial dysfunction and oxidative stress (Miyazaki & Asanuma, 2008)