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GSTs can be induced by structurally unrelated compounds known to result in chemical stress and carcinogenesis including, phenobarbital, planar aromatic compounds, ethoxyquin, BHA, and trans -stilbene oxide [42]

Contributing factors include defects in the electron transport chain, environmental toxins, inflammatory cytokines, reduced MnSOD activity, glutathione depletion, and impaired thioredoxin function

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Medicinal mushrooms, including reishi and cordyceps, have demonstrated immunostimulatory properties, offering a holistic approach to immune support