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Yuan Y, Zhang X, Zeng X, Liu B, Hu F, Zhang G

A prospective, placebo-controlled, randomized, single-blind phase II trial was conducted in a multidisciplinary university hospitals ICU where two groups of patients with systemic inflammatory response syndrome aged more than 18 years were randomized to receive either placebo or intravenous Se as a bolus-loading dosage of 2000 g Se followed by a continuous infusion of 1600 g Se per day for ten days, the study revealed that Se supplementation improved illness severity, and reduces the risk of VAP [90]

doi: 10.1016/j.nbd.2013.08.003, 91 MiyazakiI.MurakamiS.TorigoeN.KitamuraY.AsanumaM