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CRF (corticotropin-releasing factor) antagonists, which block stress signaling, normalize both HPA axis function and depressive behaviors in these models, suggesting CRF hyperactivation mediates ethanols stress-sensitizing effects (Huang et al

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Importantly, BPC 157, but not PDGF-BB, stimulated earlier maturation of granulation tissue, soluble collagen concentration in the exudates (using sponge implantation), and organized collagen significantly more in wounds (i.e., on day 12 after daily treatment) (Tkalcevic et al., 2007)