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The treatment is generally well-tolerated with few side effects

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These observations underscore the involvement of the hypoxic microenvironment in MS-associated vascular pathology, implying that strategies aimed at improving vascular oxygenation, mitigating immunoinflammatory damage, downregulating vasoactive substances, and reversing vascular abnormalities may reduce ischemic damage to the skin and visceral organs

also known as LXR), peroxisome proliferator-activated receptor (PPAR), and one cut homeobox 1 (ONECUT1