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Thats why athletes are more susceptible to illness during periods of intense training

Increased GH-release: K Raun et al

Detoxification and breaking down substances: Methylation is essential in the nervous system, in the production and breakdown of neurotransmitters, and in detoxifying some specific environmental toxicants such as arsenic

GLP-1RAs downregulate inducible NOS (iNOS) and dual oxidase 1 (DUOX1), both of which contribute to oxidative stress and epithelial damage [65, 116, 126]

Second, it modulates the NF-B signaling pathway, which is closely associated with inflammation, by inhibiting RNA polymerase II activity, leading to decreased NF-B-mediated gene transcription and a reduction in the expression of pro-inflammatory factors such as VCAM-1, TGF-, C3, and CD40