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Ensure proper injection techniques and sites to maximize effectiveness

If recurring lower abdominal pain, bloating, irregular bowel habits, or a previous diverticulitis episode that was treated but never fully investigated have been a concern, a comprehensive gut assessment is a practical starting point

Use sterile equipment for the reconstitution step, and use a new sterile insulin syringe for each injection

Advise patients using combined hormonal contraceptives to use an effective alternative contraceptive method or an additional barrier method of contraception [see Drug Interactions (7.3)]

Foundation - What Tirzepatide Already Provides Tirzepatide is the strongest FDA-approved single drug for obesity, outperforming semaglutide in head-to-head trials