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Sinomenine ameliorates cardiac hypertrophy by activating Nrf2/ARE signaling pathway

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Conclusion LC supplementation at a dose of 1000 mg/d was associated with a significant reduction in oxidative stress and an increase in antioxidant enzymes activities in CAD patients

Because of its broader receptor activity, it may theoretically have more pronounced effects on reward and energy pathways, though human data on libido effects remain limited