10.1016/j.biopha.2023.115752 135 YaS.WenL.Yong-linW.Zi-pengG.QunW.Yong-junL.et al (2019)
Briefly, 1-palmitoyl-2-oleoyl-glycero-3-phosphocholine (PC, Avanti Polar Lipids, 850457), 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (PE, Avanti Polar Lipids, 850757), and liver L--phosphatidylinositol (Liver PI, Avanti Polar Lipids, 840042) in chloroform were mixed at a 5:2:1 (w/w) ratio for Figure 3d and Extended Data Figure 4l, or PC:PE were mixed at a 5:2 (w/w) ratio for Extended Data Figure 7f
And while hydrophilic (water-attracting) molecules can be kept inside the encapsulated core, hydrophobic (water-repelling) substances can dissolve into the phospholipid membrane itself - in this way, liposomes can transport both hydrophilic and hydrophobic molecules
Glycogen accumulationhepatocytes not markedly enlarged
At the same time, it inhibits lipogenesis, the process by which your body creates and stores new fat