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Typically, intramuscular injections might be given daily during the first week, followed by weekly shots for one month, and then every month or two months for life

The intracellular domain of LRP-1 (LRP-1-ICD) was found upregulated in capillaries from mice 6 months after PFF injection [273]

Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S (2011) Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis

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