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The approval is the third for Balfaxar, which is already marketed in Canada and the EU as octaplex

The mechanism was proposed to involve copper-dependent enzymes (notably lysyl oxidase, which catalyzes the cross-linking of collagen and elastin and requires copper as a cofactor), GHK-specific effects on growth factor activity, and downstream gene-expression effects in fibroblasts and other tissue-repair-relevant cell types

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