Banerjee PG, Paul A, Chakraborty A, Kundu S
Biomaterials 2026 , 325 , 123622
Milk Thistle Side Effects And Safety Common Side Effects Milk thistle appears to be well-tolerated but can cause mild digestive symptoms, such as: Bloating, fullness, gas, or stomach pain Heartburn Nausea Changes in bowel habits Diarrhea Rare Side Effects Stop taking milk thistle and seek emergency medical care if you develop signs and symptoms of allergic reactions: Skin reactions (rash, hives, itching, eczema) Severe allergic reaction (anaphylaxis), including throat tightening, swelling, and difficulty breathing Warning: The risk of an allergic reaction to milk thistle is higher in people who are allergic to related plants such as ragweed, marigold, daisy, and chrysanthemum
However, it has also been shown to reduce body fat in healthy individuals
Skin Sensitivity Tests : A patch test can help gauge the risk of allergic reactions, especially for topical peptides