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Peptides containing free thiol group may oxidize to form dimers or oligomers during storage, even as the lyophilized dry powder at a low temperature

Penna C, Mancardi D, Rastaldo R, et al

Cerebrolysin is one of the most extensively studied neuropeptide preparations in clinical medicine, with data from more than 200 clinical trials and approximately 15,000 patients across multiple neurological conditions

At the cellular interface, dermal fibroblasts regulate spreading, migration, and extracellular matrix (ECM) turnover through integrin-dependent adhesion signaling (e.g., FAK/ERK pathways), which is central to fibroblastECM homeostasis [48]

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