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As discussed in the FY 2023 IPPS/LTCH PPS final rule (87 FR 48939) and in previous rulemaking, the intent of section 1886(d)(5)(K) of the Act and regulations under 412.87(b)(2) is to pay for new medical services and technologies for the first 2 to 3 years that a product comes on the market, during the period when the costs of the new technology are not yet fully reflected in the MS-DRG weights (69 FR 49002)

Beutler E, Moroose R, Kramer L, Gelbart T, Forman L: Gamma-glutamylcysteine synthetase deficiency and hemolytic anemia

German Nutrition Society (DGE)

Our data suggest that choline can promote liver health by maintaining cholesterol homeostasis.10 Choline induces glucose and insulin intolerance in Pemt(-/-) mice through modulating plasma glucagon and its action in liver.11 Choline supplementation decreased the concentration of liver triacylglycerol during the first 4 wk after parturition