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Looking ahead, by optimizing delivery systems, exploring combination therapies (such as SIRT1 with GLP-1 agonists), incorporating SIRT1 gene polymorphisms for personalized treatment, and validating long-term safety, SIRT1 has the potential to evolve from a "promising target" to a "transformative therapy." SIRT1 deacetylates forkhead box class O3 (FOXO3), thereby initiating autophagy

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The nature of IV therapy directly impacts cost: Rapid absorption means higher-quality, sterile solutions are needed, which cost more