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Increasing dosage of thyroid replacement medication will not help because the body is not getting the T3 that the body really needs

This high metabolic rate leads to increased production of reactive oxygen species (ROS) as byproducts of cellular respiration.Presence of Redox-Active Metals: The brain contains transition metals such as iron and copper, which can catalyze the formation of highly reactive hydroxyl radicals through the Fenton reaction.Limited Regenerative Capacity: Unlike some other tissues, neurons have limited regenerative capacity

Still, the benefits of treating deficiency usually outweigh the increased chance of bruising

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Aging (Albany NY) 13(7):9582 Gao X, Wang B, Huang Y, Wu M, Li Y, Li Y, Zhu X, Wu M (2023) Role of the Nrf2 signaling pathway in ovarian aging: potential mechanism and protective strategies