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Non-human primate models In non-human primates (NHPs), infection with SARS-CoV, MERS-CoV or SARS-CoV-2 results in viral spread to multiple tissues, including lungs 121,122,123

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The integrity of the PR layer is heavily influenced by the retinal pigment epithelium (RPE), which consists of cells with sheet-like microvilli that interact with the outer PR segments extending from the outer retinal surface [172,173]