Part 1: Debbag R, Avila-Aguero ML, Brea J, Espinal C, Romero-Feregrino R, Torres JR, Vazquez H, Cuadros R, Lazo-Paez G, Schilling A, Bonvehi P, Kairalla M, Rodriguez-Morales AJ
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In the 72-week non-diabetic obesity trial, adults lost -15.0% at 5 mg, -19.5% at 10 mg, and -20.9% at 15 mg. Real-world outcomes vary because dose reached, adherence, and baseline state vary
The therapy effect was ascribed to the counteraction of the congestion of major vessels, and particularly to activation of the rescuing collaterals, i.e., azygos vein direct blood flow delivery