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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

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Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

In a subsequent human clinical study published in Redox Biology, researchers at the University of New South Wales investigated the bioavailability of oral Glyteine supplementation

For peptide research, you simply use the volume markings