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Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability

Research examining lasting neuroplastic changes rather than acute cognitive effects has successfully employed administration frequencies as low as three times weekly (every other day or Monday/Wednesday/Friday patterns) with outcomes comparable to daily dosing

In addition to supporting synaptic and intrinsic neuronal properties in the hippocampus, hippocampal adult neurogenesis appears to be important for cognitive performance 23,24,25,26 and behavior during stress and depression 27,28

2021 Mar;42(3):305-13