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The latter is a competitor of 2-Oxoglutarate-dependent dioxygenases such as Ten-eleven translocation methylcytosine dioxygenase and therefore induces DNA hydroxymethylation and gene upregulation 52

This result was in agreement with (Xu et al., 2023), who previously demonstrated the ability of PA to alleviate structural liver damage in CCL4-induced hepatoxicity in mice

The combination of hepsin with NAC shows a synergistic effect, providing more effective protection than NAC alone, thus offering new avenues for enhancing current treatment approaches

FSH and E2 synergistically encourage GCs to create LHR in preparation for the subsequent LH signal

It is also not excluded that the same supplementation protocol without training program may induce different response in SPARC and decorin levels