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Simultaneous quantification of these two oxidized metabolites by electrochemical HPLC assay demonstrated that human P450 2E1 selectively oxidizes APAP to NAPQI (determined as glutathione conjugate, GS-APAP), whereas human P450 2A6 selectively oxidizes APAP to 3-OH-APAP (Chen et al., 1998)

Age and multiparity related urethral sphincter muscle dysfunction in a rabbit model: Potential roles of TGF- and Wnt- catenin signaling pathways

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Glutathione plays a critical role in the function of mitochondria (the energy-producing compartments in cells)

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