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BCAAs in disease Metabolic disease Existing studies point out that BCAAs and their metabolites are the strongest biomarkers of metabolic diseases such as obesity, insulin resistance, and type 2 diabetes (T2D)

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For topical or in vivo investigational use, concentrations of 0.05% to 0.1% (w/v) have been employed in wound-healing studies without reported adverse events

Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ

10.1016/j.fct.2011.04.011 123 ZhouY.FanX.JiaoT.LiW.ChenP.JiangY.et al (2021)