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Laminarin strongly inhibits VEGF-driven neovascularization in ectopic tissues, reduces endothelial tube formation, and induces volumetric regression of established lesions, thereby limiting EMs progression at both molecular and anatomical levels ( In vitro studies show that kelp-derived polysaccharides, including laminarin, reduce calcium dyshomeostasis by preventing pathological mitochondrial Ca 2+ overload, which is a major trigger of mPTP opening, cytochrome c release, and intrinsic apoptosis

doi: 10.1002/jcp.27524 [DOI] [PubMed] [Google Scholar] 143.Islam MS, Giampieri F, Janjusevic M, et al

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Diagnosis Your doctor will first take a detailed medical history