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It is not a drug, dietary supplement, food additive, cosmetic, or therapeutic agent, and must not be used in or on humans or animals

In research environments, it is of interest for investigations involving biochemical signaling pathways, compound stability, and molecular characterization

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When NNMT is overactive, it consumes S-adenosylmethionine (SAM) and reduces levels of nicotinamide adenine dinucleotide (NAD+), a critical coenzyme involved in cellular energy production

However, there is no strong scientific evidence to suggest that B12 injections directly lead to increased fat burn or significantly impact metabolism for people who are not deficient