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Despite encouraging preclinical findings, clinical data are currently absent, and prioritization of early-phase human trials is necessary before any definitive conclusions can be drawn

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Thereafter, the cells were immediately detected by flow cytometer

To cope with the elevated oxidative stress they generate, cancer cells enhance their antioxidant capacity, largely through sustained activation of the transcription factor NRF2 often driven by mutations in its negative regulator KEAP1

Posner MI, Petersen SE (1990)