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J Inherit Metab Dis 42:1019-1029

The weight loss peptide category, including tesofensine and related compounds, represents one of the fastest-growing applications for sublingual peptide delivery

GLP-1s and other FDA-approved drugs have objective markers to establish whether they actually work, such as HbA1c levels for blood sugar and measurable weight loss

This shows up on an IGE test, which I do all the time

Furthermore, while animal and cell line studies provide valuable mechanistic insights, their findings cannot be directly extrapolated to human physiology, underscoring the critical need for more human-specific mechanistic research