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This regulation is crucial because actin drives cell migration, the process by which cells move to injury sites to begin repair

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[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Snchez-Martn P., Saito T., Komatsu M

Dit proces, aangestuurd door het Arp2/3-complex en gerelateerde signaalroutes waaronder focale adhesiekinase (FAK) en PI3K/Akt, is essentieel voor de gerichte migratie van fibroblasten, endotheelcellen en immuuncellen naar de locatie van letsel

Instead, they are activated by damage-associated molecular patterns released from neighboring cardiomyocytes or ECs undergoing cuproptosis