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this enzyme is widely distributed and plays an essential role in de novo gluconeogenesis and lipogenesis (Jitrapakdee and Wallace, 1999)

Oral supplementation or consumption of fortified foods is usually sufficient and first-line

Chemical models of HCC have demonstrated a direct link between alcohol consumption, macrophage activation, and increased HCC risk

Hence, local application of melatonin to peripheral nerves, i.e., via intraneural injections or polymer tube nerve reconstruction grafts filled with the therapeutic substance (see Jakovcevski et al., 2022), deems to be a more appropriate application method

doi: 10.4103/2319-4170.128725 210 Panner SelvamMHenkelRSharmaRAgarwalA