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Critically, AOD-9604 did not produce the metabolic side effects associated with full-length growth hormone, including no insulin resistance or glucose intolerance, no elevation of IGF-1 levels, no fluid retention or joint pain, and no cardiovascular parameter changes

By inhibiting the NNMT enzyme, 5-Amino-1MQ supports reduced fat storage and enhanced energy metabolism

Gastrointestinal side effects (nausea, vomiting, diarrhea) occur in 3050% of tirzepatide users during dose titration and typically resolve within 48 weeks

Only involved researchers have access to data when they are to be analysed