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More than half of patients with alcoholism exhibit impaired intestinal barrier function and microbial imbalance 40,41

The repair signature is reminiscent of the copper signature very recently demonstrated in regulatory T cells, whose energetic and functional phenotype is highly dependent on free intracellular copper

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Hossain A, Bhutia KL, Pramanick B, Maitra S, Ibrahimova U, Kumari VV, Ahmad Z, Uzair M, Aftab T (2022) Glutathione in higher plants: biosynthesis and physiological mechanisms during heat and drought-induced oxidative stress

Chromium also appears to be involved in the metabolism of carbohydrates, fats, and protein