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doi: 10.3389/fonc.2026.1740352 Received 05 November 2025 Revised 28 December 2025 Accepted 13 January 2026 Published 30 January 2026 Volume 16 - 2026 Edited by Felipe DAlmeida Costa, A

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Other symptoms may include: Stiffness Swelling Redness Limited range of motion If you experience any of the following symptoms, seek medical attention promptly: Fever over 102F (38.89C) Swelling, redness, and warmth in the affected area General illness or pain in multiple areas Difficulty moving the joint Pain lasting longer than two weeks While bursitis cannot always be prevented, there are steps you can take to reduce your risk: Use cushions or pads when resting a joint on a hard surface Vary your activities and warm up before exercising Start new exercises slowly and gradually increase intensity Take frequent breaks when performing repetitive motions Maintain good posture throughout the day Use orthotic shoe inserts to correct leg length discrepancies Maintain a healthy body weight Stop activities that cause pain and consult your doctor To diagnose bursitis, your doctor will ask about your symptoms and perform a physical exam to check for joint swelling

It is not a DEA-scheduled substance, so possession is not illegal but it also cannot be legally marketed as a drug or dietary supplement

It helps promote healing in: TB-500 plays a key role in tissue regeneration