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The sample size calculation was based on volume expansion, where 500 ml of saline is usually associated with a mean SV change of 25% (+/10%) for a mean baseline of 40 10 ml ( p- value of 0.05

Hydrate well and limit alcohol to protect the lining

Table 7

Theres no question that the use of many of these has surged, in part because of their putative anti-aging effects or other unsubstantiated health claims, along with endorsements by celebrities, longevity, and wellness influencers