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Most of the clonal expansion drivers are depleted targets in the screen, reflecting the role of the gene product in promoting cell fitness, as is the case for Kras (Fig

When endothelial cells are activated and destabilized during inflammation, vascular permeability is increased, resulting in vascular abnormalities and activation of the coagulation cascade [21]

In clinical MRSA strains, the MIC decreased from 8 g/ml when using regular teicoplanin to 0.125 g/ml when using teicoplanin-aptamer-PLGA nanoparticles [210]