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In the GBM microenvironment, aberrantly upregulated MMP activity and an imbalance with their natural inhibitor, tissue inhibitor of metalloproteinases-1, lead to degradation and loss of agrin, a key component of the perivascular basal lamina

Sleep disorders like obstructive sleep apnea, common in patients with obesity, should be evaluated and treated as they significantly impact weight management success

Over-the-counter pain relievers like acetaminophen or ibuprofen can ease muscle aches