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2 Materials and methods 2.1 Protocol and registration This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement (Moher et al., 2009) and the guidelines from the Cochrane Handbook for Systematic Reviews of Interventions (Higgins and Green, 2008)

Histological analysis revealed reduced lesion size, decreased neuronal loss, and improved tissue preservation at the injury site

When NNMT is inhibited by compounds like 5-Amino-1MQ, more nicotinamide becomes available for conversion to NAD+ via NAMPT

Using the correct dosage can reduce these B12 lipo injection side effects and make the treatment enjoyable

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