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The dosage and treatment frequency are tailored based on the individuals skin tone, pigmentation level, health status, and desired outcomes

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Treatment should be continued despite this flare unless there is clinical or biochemical evidence of decompensation

[7] The protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell death and increases resistance to toxic challenges, especially oxidative stress