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Proton pump inhibitors (PPIs) and H2-receptor antagonists (H2RAs) are commonly prescribed after bariatric surgery and can impair the release of B12 from food proteins, reducing absorption of food-bound B12 over time

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It is studied as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to metabolic and oncogenic pathways in research models

Additional studies are needed ( Age-related macular degeneration Age-related macular degeneration is a condition that causes you to gradually lose central vision, usually in both eyes