In response to various stimuli, endolysosome damage leads to the formation of specific cellular elements via efficient LQC, which includes lysosomal repair, lysophagy, and lysosomal regeneration 26 (Fig
In a randomized, double-blind, placebo-controlled trial, daily supplementation with Lactobacillus plantarum ECGC 13110402 for 12 weeks in adults with moderate hypercholesterolemia resulted in a significant reduction in LDL cholesterol and hs-CRP compared to placebo, suggesting a direct benefit of probiotics on cardiovascular risk markers in humans (Zhou et al., 2023)
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Its important to inquire about underlying causes of gut dysfunction such as poor diet, medication use (eg, antibiotics, nonsteroidal anti-inflammatory medications, proton pump inhibitors, antacids, etc), an excessively clean and hygienic environment, psychological stress, and environmental toxins
10.3390/life15010078 80 SalehiP.AkinpeluO