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Increased Receptor Affinity (Hypothesized): Some research suggests that the lack of the N-terminal tripeptide actually enhances its binding affinity to the IGF-1R in damaged or targeted cells, leading to a strong, immediate growth signal that promotes satellite cell recruitment, repair, and growth

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doi: 10.1016/0028-2243(83)90220-4 188 PomorskiMZimmerMFlorjanskiJMichniewiczJWiatrowskiAFuchsTet al

Among them, GPX4 is a membrane-associated phospholipid hydroperoxidase, and it is also the only enzyme in the GPX family that directly reduces and destroys lipid hydroperoxides, which can reduce complex lipid compounds in addition to reducing H 2 O 2 and small molecule hydroperoxides