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Our observations imply that sulforaphane may not directly affect autophagy at the concentration and over the time course associated with neuroprotection that we used, but it can still rescue rotenone-inhibited autophagy

Adenosine 3,5-monophosphate in rat uterus: acute elevation by estrogen

Your protocol planning should account for this shift and set appropriate expectations for the second half of treatment

The primary way SF protects BBB integrity appears to be through its activation of the Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NRF2) pathway, since BBB integrity is rapidly compromised in the absence of Nrf2 transcriptional activity [32]

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