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The sum of these findings suggests that reduced glutathione selectively disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization, probably serving as a putative model for oculocutaneous albinism type 4

Rating TV-14 Genre Reality,Documentary Original Language English Release Date Feb 22, 2024

Compared with the control group, ear thickness and weight were significantly increased in the model group, indicating inflammatory swelling, which was markedly reduced following treatment with either BHG or dexamethasone ( Figure 3D )