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This, in turn, can narrow the arteries, leading to reduced blood flow

Dihexa is orally bioavailable in animal models, with cognitive effects comparable to subcutaneous injection a property virtually absent among conventional neuropeptides that require intranasal or injectable delivery (PMID: 23055539)

While microglia are the main cells linked to physiological myelin phagocytosis, and astrocytes to pathologic phagocytosis in sclerosis plaques, a feature which will be discussed later, oligodendrocytes are the generators of CNS myelin

Typical weekly range: 28 mg once weekly (gradual escalation over 812 weeks)