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In Season 5, with Spike having moved from Villain to Anti-Hero, the writers humorously make a point that his smoking isn't stupid only because he's already dead: Xander says as Spike lights a cigarette, "Those things'll kill you" and Spike gives him a look as a reminder that he's already dead

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If youre in the way, youre out

The study findings demonstrate that reduced-nicotine cigarettes could be an essential public health measure to reduce tobacco addiction

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