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rhamnosus LR-32, and L

J Pharmacol Sci

Acta Paediatr Scand 78(6):879884

In PCOS patients, ovarian granulosa cells frequently exhibit elevated oxidative stress markers ( e.g ., malondialdehyde, MDA) alongside reduced activity of antioxidant enzymes ( e.g ., superoxide dismutase, SOD, and glutathione peroxidase 4, GPX4)

P2Y 2 receptor agonists, denufosol (OLIYNYK et al., 2010), were promising for their ability to activate alternative chloride secretion pathways, but both of these agonists have not been pursued further due to not meeting primary study goals of improving FEV 1 (Ratjen et al., 2012) and having a narrow effective concentration range, respectively (OLIYNYK et al., 2010)